Home/GT Families/GT61/Eogt
Eogt
Mus musculus · EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255)
GT61Non-model organism · annotation 4–5Fold GT-BInverting1 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT61 · CAZy entry |
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| Gene symbol | Eogt |
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| Synonyms / alternate names | - Aer61
- Eogt1
- Extracellular O-linked N-acetylglucosamine transferase
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| UniProt accession | Q8BYW9 |
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| NCBI Gene ID | 101351 |
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| Source species | Mus musculus |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) |
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| Subcellular location | Endoplasmic reticulum lumen |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | 9WJK |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-glucosamine |
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| Donor CCD code(s) | UD1 |
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| Acceptor substrate(s) | - L-seryl-[protein]
- L-threonyl-[protein]
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
527 aa
MLMLLVFGVLLHEVPLSGQDKAHSEADDAPGKALYDYSSLRLPAEHIPFFLHNNRHVASVCREDSHCPYKKHLENLNYCWGYEKSCAPEFRFGSPVCSYVDLGWTDTLESAQDMFWRQADFGYARERLGEIRTICQPERASDSSLVCSRYLQYCRATGLYLDLRNIKRNHDRFKEDFLQGGEIGGYCKLDSHALVSEGQRKSPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHVNNSFSTDVYIVMWDTSTYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNITQEGPKDGKVRVTILARSTEYRKILNQDELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIHYITWRKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWPFKKKHDEL
Catalytic domain sequence
105 aa
NTGLFRAFSQHVLHRLNITQEGPKDGKVRVTILARSTEYRKILNQDELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAV
