Home/GT Families/GT66/aglB1
aglB1
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) · Dolichyl-phosphooligosaccharide-protein glycotransferase 1 (EC 2.4.99.21)
GT66Model organism · annotation ≥ 4Fold GT-CInverting2 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT66 · CAZy entry |
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| Gene symbol | aglB1 |
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| Synonyms / alternate names | - Archaeal glycosylation protein B
- Oligosaccharyl transferase
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| UniProt accession | Q8U4D2 |
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| NCBI Gene ID | not curated |
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| Source species | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
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| Taxonomic domain | Archaea |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Dolichyl-phosphooligosaccharide-protein glycotransferase 1 (EC 2.4.99.21) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-C |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mn2+, Mg2+) |
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| Oligomeric state | not curated |
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| PDB structures | 2ZAG, 2ZAI |
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Donor and acceptor specificity
| Sugar nucleotide donor | not curated |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | - an archaeal dolichyl phosphooligosaccharide
- [protein]-L-asparagine
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
967 aa
MVKTQIKEKKKDEKVTIPLPGKIKTVLAFLVVLAFAAYGFYIRHLTAGKYFSDPDTFYHFEIYKLVLKEGLPRYYPMADAPFGSLIGEPLGLYILPAIFYKIISIFGYNELEAFLLWPPFVGFLSVIGVYLLGRKVLNEWAGMWGAIILSVLTANFSRTFSGNARGDGPFMMLFTFSAVLMLYYLTEENKNKKIIWGTLFVLLAGISTAAWNGSPFGLMVLLGFASFQTIILFIFGKINELREFIKEYYPAYLGILAISYLLTIPGIGKIGGFVRFAFEVFLGLVFLAIVMLYGGKYLNYSDKKHRFAVVAVIVIAGFAGAYIYVGPKLFTLMGGAYQSTQVYETVQELAKTDWGDVKVYYGVEKPNGIVFFLGLVGAMIVTARYLYKLFKDGRRPHEELFAITFYVMSIYLLWTAARFLFLASYAIALMSGVFAGYVLETVEKMKESIPIKAALGGVIAIMLLLIPLTHGPLLAQSAKSMRTTEIETSGWEDALKWLRENTPEYSTATSWWDYGYWIESSLLGQRRASADGGHARDRDHILALFLARDGNISEVDFESWELNYFLVYLNDWAKFNAISYLGGAITRREYNGDESGRGAVTTLLPLPRYGEKYVNLYAKVIVDVSNSSVKVTVGDRECDPLMVTFTPSGKTIKGTGTCSDGNAFPYVLHLTPTIGVLAYYKVATANFIKLAFGVPASTIPGFSDKLFSNFEPVYESGNVIVYRFTPFGIYKIEENINGTWKQVYNLTPGKHELKLYISAFGRDIENATLYIYAINNEKIIEKIKIAEISHMDYLNEYPIAVNVTLPNATSYRFVLVQKGPIGVLLDAPKVNGEIRSPTNILREGESGEIELKVGVDKDYTADLYLRATFIYLVRKSGKDNEDYDAAFEPQMDVFFITKIGENIQLKEGENTVKVRAELPEGVISSYKDELQRKYGDKLIIRGIRVEPVFIAEKEYLMLEVSASAPHH
Catalytic domain sequence
403 aa
LTAGKYFSDPDTFYHFEIYKLVLKEGLPRYYPMADAPFGSLIGEPLGLYILPAIFYKIISIFGYNELEAFLLWPPFVGFLSVIGVYLLGRKVLNEWAGMWGAIILSVLTANFSRTFSGNARGDGPFMMLFTFSAVLMLYYLTEENKNKKIIWGTLFVLLAGISTAAWNGSPFGLMVLLGFASFQTIILFIFGKINELREFIKEYYPAYLGILAISYLLTIPGIGKIGGFVRFAFEVFLGLVFLAIVMLYGGKYLNYSDKKHRFAVVAVIVIAGFAGAYIYVGPKLFTLMGGAYQSTQVYETVQELAKTDWGDVKVYYGVEKPNGIVFFLGLVGAMIVTARYLYKLFKDGRRPHEELFAITFYVMSIYLLWTAARFLFLASYAIALMSGVFAGYVLETVEKMKE
