Home/GT Families/GT7/V9LFM6
V9LFM6
Callorhinchus milii · Beta-1,4-galactosyltransferase 3 (EC 2.4.1.275; 2.4.1.38; 2.4.1.90)
GT7Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT7 · CAZy entry |
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| Gene symbol | not curated |
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| Synonyms / alternate names | - Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
- N-acetyllactosamine synthase
- Nal synthase
- Neolactotriaosylceramide beta-1,4-galactosyltransferase
- UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3
- UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3
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| UniProt accession | V9LFM6 |
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| NCBI Gene ID | not curated |
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| Source species | Callorhinchus milii |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Beta-1,4-galactosyltransferase 3 (EC 2.4.1.275; 2.4.1.38; 2.4.1.90) |
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| Subcellular location | - Golgi apparatus
- Golgi stack membrane
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-galactose |
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| Donor CCD code(s) | GDU |
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| Acceptor substrate(s) | - N-acetyl-D-glucosamine
- a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))
- a beta-D-glucosylceramide
- a neolactoside IV(3)-beta-GlcNAc-nLc4Cer
- an N-acetyl-beta-D-glucosaminyl derivative
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
180 aa
CGVREALKDEDWDCLFLHDVDLIPENDNNLYVCNDQYPKHVSSAMNKFKYRLPYRMYFGGVSALTPEQYLKMNGFPNTYWGWGGEDDDISARIYLSGMKIIRTPISLGHYKMIMHDMDKGNEKNEKRFDLLVKVSRSWKFDGMNSVEYKILKKEEFPLYTNITADIGIDPRLRMKLHPKK
Catalytic domain sequence
78 aa
KHVSSAMNKFKYRLPYRMYFGGVSALTPEQYLKMNGFPNTYWGWGGEDDDISARIYLSGMKIIRTPISLGHYKMIMHD
