Home/GT Families/GT8/GXYLT2
GXYLT2
Homo sapiens · Glucoside xylosyltransferase 2 (EC 2.4.2.42)
GT8Model organism · annotation ≥ 4Fold GT-ARetaining
External resources
Identification and annotation
| CAZy family | GT8 · CAZy entry |
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| Gene symbol | GXYLT2 |
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| Synonyms / alternate names | - GLT8D4
- Glycosyltransferase 8 domain-containing protein 4
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| UniProt accession | A0PJZ3 |
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| NCBI Gene ID | 727936 |
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| Source species | Homo sapiens |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Glucoside xylosyltransferase 2 (EC 2.4.2.42) |
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| Subcellular location | Membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Retaining |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-xylose |
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| Donor CCD code(s) | UDX |
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| Acceptor substrate(s) | 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
443 aa
MKLRSKAAALLLLALAALLLALLSLRAGRAEPPALPARPASAPQRHPAPVPARWPGPGALPGASPGVRRRRPPRPRPRAGRRGAARLEKLARRPGEPRSFQAVLPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKIQFHIFTEDSLKPEFDKQLRQWPDSYTKKFEHRIYPITFSVGNPQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPVDDIWKLLRLFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSTQFKNSMIPTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHCMYGSNCREAEHEGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFQDNLFQSMYYPLQLKFLETVHTLCGRIPQVFLKQIEKTMKRAYEKHVIIHVGPNQMH
Catalytic domain sequence
230 aa
AVVACGNRLEETLVMLKSAVLFSHRKIQFHIFTEDSLKPEFDKQLRQWPDSYTKKFEHRIYPITFSVGNPQEWKKLFKPCAAQRLFLPVILKDVDSLLYVDTDVLFLRPVDDIWKLLRLFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNLTRIRSTQFKNSMIPTGLAWEDMLYPLYQKYKNAITWGDQDLLNIIFYFNPECLYVFPCQWNYRPDHC
