Home/GT Families/GT8/GYG1
GYG1
Homo sapiens · Glycogenin-1 (EC 2.4.1.186)
GT8Model organism · annotation ≥ 4Fold GT-ARetaining23 PDB structure(s)
External resources
Identification and annotation
| CAZy family | GT8 · CAZy entry |
|---|
| Gene symbol | GYG1 |
|---|
| Synonyms / alternate names | GYG |
|---|
| UniProt accession | P46976 |
|---|
| NCBI Gene ID | 2992 |
|---|
| Source species | Homo sapiens |
|---|
| Taxonomic domain | Eukaryota |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | Glycogenin-1 (EC 2.4.1.186) |
|---|
| Subcellular location | |
|---|
Structure and mechanism
| Fold type | GT-A |
|---|
| Catalytic mechanism | Retaining |
|---|
| Cation dependence | Yes (Mn2+) |
|---|
| Oligomeric state | tetramer |
|---|
| PDB structures | 3Q4S, 3QVB, 3RMV, 3RMW, 3T7M, 3T7N, 3T7O, 3U2T, 3U2U, 3U2V, 3U2W, 3U2X, 6EQJ, 6EQL, 7OVX, 7Q0B, 7Q0S, 7Q12, 7Q13, 7ZBN, 8CVX, 8CVY, 8CVZ |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-glucose |
|---|
| Donor CCD code(s) | UPG |
|---|
| Acceptor substrate(s) | - L-tyrosyl-[glycogenin]
- [1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin]
|
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
350 aa
MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMDADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFDGGDQGILNTFFSSWATTDIRKHLPFIYNLSSISIYSYLPAFKVFGASAKVVHFLGRVKPWNYTYDPKTKSVKSEAHDPNMTHPEFLILWWNIFTTNVLPLLQQFGLVKDTCSYVNVLSDLVYTLAFSCGFCRKEDVSGAISHLSLGEIPAMAQPFVSSEERKERWEQGQADYMGADSFDNIKRKLDTYLQ
Catalytic domain sequence
216 aa
VTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVSDSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMDADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFDGGDQGILNTFFSSWATTDIRKHLPFIYNLSSISIYSYLPAFKVFGASAKVVHFLGRVKPWNY
