Home/GT Families/GT2/QTGAL
QTGAL
Homo sapiens · Queuosine-tRNA galactosyltransferase (EC 2.4.1.-)
GT2Model organism · annotation ≥ 4Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT2 · CAZy entry |
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| Gene symbol | QTGAL |
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| Synonyms / alternate names | - B3GNT8
- B3GNTL1
- Beta-1,3-N-acetylglucosaminyltransferase 8
- UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1
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| UniProt accession | Q67FW5 |
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| NCBI Gene ID | 146712 |
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| Source species | Homo sapiens |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | Queuosine-tRNA galactosyltransferase (EC 2.4.1.-) |
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| Subcellular location | Cytoplasm |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-galactose |
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| Donor CCD code(s) | GDU |
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| Acceptor substrate(s) | queuosine(34) in tRNA(Tyr) |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
346 aa
MQAHVSIILPVHNAEPWLDECLRSVLQQDFEGTMELSVFNDASKDKSGAIIEKWRVKLEDSGVHVIIGGHDSPSPRGVGYAKNQAVAQSSGSYLCFLDSDDVMMPQRVRLQHEAAVQHPSSIIGCRVRRDPPNSTERYTRWINQLTPEQLLTQVFTSNGPTVIMPTWFCSRAWFSHVGPFNEGGQGVPEDLLFFYEHLRKGGGVIRVDQSLLLYRHHPQAATHCVLETTIWTHRVRFLEEQALPRWAAFTIWNAGKQGRRLYRSLTAGSQRKVVAFCDVDENKIRKGFYCHEDSQERPKPRIPILHFRAARPPFVICVKLDLTGGAFEDNLRSLHLQEGQDFLHFS
Catalytic domain sequence
172 aa
SIILPVHNAEPWLDECLRSVLQQDFEGTMELSVFNDASKDKSGAIIEKWRVKLEDSGVHVIIGGHDSPSPRGVGYAKNQAVAQSSGSYLCFLDSDDVMMPQRVRLQHEAAVQHPSSIIGCRVRRDPPNSTERYTRWINQLTPEQLLTQVFTSNGPTVIMPTWFCSRAWFSHV
