Home/GT Families/GT2/wbbL
wbbL
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) · N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase (EC 2.4.1.289)
GT2Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT2 · CAZy entry |
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| Gene symbol | wbbL |
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| Synonyms / alternate names | - wbbL1
- Rhamnosyltransferase WbbL
- dTDP-Rha:alpha-D-GlcNAc-pyrophosphate polyprenol, alpha-3-L-rhamnosyltransferase
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| UniProt accession | P9WMY3 |
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| NCBI Gene ID | 888714 |
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| Source species | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 5 |
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Function and localisation
| Enzyme function | N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase (EC 2.4.1.289) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mn2+, Mg2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | dTDP-beta-L-rhamnose |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | - N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans
- octa-cis-decaprenol
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
307 aa
MTDVLPVVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAHSTGRDPASHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVRSSLRRSRRRKLKLVEGRH
Catalytic domain sequence
230 aa
VVAVTYSPGPHLERFLASLSLATERPVSVLLADNGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDAGEPWVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPSARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGSCLLVRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHH
