Home/GT Families/GT30/waaA
waaA
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) · 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12)
GT30Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT30 · CAZy entry |
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| Gene symbol | waaA |
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| Synonyms / alternate names | - kdtA
- Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Monofunctional Kdo transferase
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| UniProt accession | P44806 |
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| NCBI Gene ID | not curated |
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| Source species | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
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| Taxonomic domain | Bacteria |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12) |
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| Subcellular location | not curated |
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Structure and mechanism
| Fold type | GT-B |
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| Catalytic mechanism | Inverting |
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| Cation dependence | No |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | CMP-3-deoxy-beta-D-manno-octulosonate |
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| Donor CCD code(s) | not curated |
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| Acceptor substrate(s) | lipid IVA (E. coli) |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
427 aa
MWRFFYTSLLLICQPLILCFIGLLSVKSPRYRQRLAERYGFYGNASCPPPQGIFIHAASVGEVIAATPLVRQLQQDYPHLSITFTTFTPTGSERVKATFGDSVFHYYLPLDLPFSIHRFINFVQPKLCIVMETELWPNLIHQLFLRNIPFVIANARLSARSAHRYGKIKAHLQTMWSQISLIAAQDNISGKRYATLGYPKEKLNITGNIKYDLNTNDELLRKIDSLRTLWKQDRPIWIAASTHNGEDEIILKSHRALLAKYPNLLLLLVPRHPERFNVVADLLKKEKFQFIRRSTNELPNENTQVILGDSMGELMLMYGISDIAFVGGSLVKHGGHNPLEPLAFKMPVITGKHTFNFPEIFRMLVEVQGVLEVNSTADALERAVEALLNSKESRERLGNAGYEVLMENRGALQRLLDLLKPYLERNV
Catalytic domain sequence
180 aa
QRLAERYGFYGNASCPPPQGIFIHAASVGEVIAATPLVRQLQQDYPHLSITFTTFTPTGSERVKATFGDSVFHYYLPLDLPFSIHRFINFVQPKLCIVMETELWPNLIHQLFLRNIPFVIANARLSARSAHRYGKIKAHLQTMWSQISLIAAQDNISGKRYATLGYPKEKLNITGNIKYD
