Home/GT Families/GT30/waaA
waaA
Chlamydophila psittaci (strain ATCC VR-125 / 6BC) · 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12; 2.4.99.13; 2.4.99.14; 2.4.99.15)
GT30Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT30 · CAZy entry |
|---|
| Gene symbol | waaA |
|---|
| Synonyms / alternate names | - gseA
- Kdo(2)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Kdo(3)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Multifunctional Kdo transferase
|
|---|
| UniProt accession | F0T4D1 |
|---|
| NCBI Gene ID | 12243067 |
|---|
| Source species | Chlamydophila psittaci (strain ATCC VR-125 / 6BC) |
|---|
| Taxonomic domain | Bacteria |
|---|
| UniProt annotation level | 5 |
|---|
Function and localisation
| Enzyme function | 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12; 2.4.99.13; 2.4.99.14; 2.4.99.15) |
|---|
| Subcellular location | not curated |
|---|
Structure and mechanism
| Fold type | GT-B |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | No |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | CMP-3-deoxy-beta-D-manno-octulosonate |
|---|
| Donor CCD code(s) | not curated |
|---|
| Acceptor substrate(s) | - lipid IVA (E. coli)
- alpha-Kdo-(2->6)-lipid IVA (E. coli)
- alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)
- alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)
|
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
433 aa
MIKGRRTKLHTFLYDCFLIFAFMVGLPRILYKRFVHGKYTKSLGIRFGFKKPEVPGTGPVAWFHGASVGETALLLPLLKRFMKEYPEWRCVVTSCTESGHENAHRLFGPLGVTTFILPLDLSIIIKPVVRAISPSLLVFSEGDCWLNFIEEAKRLGATAVIINGKLSANSCKRFTILKRFGRNYFSPVDGFLLQDEQHKARFLQLGVDKEKIQVTGNIKTYTETLSENNQRDYWREKLQLAQDTELLVLGSVHPKDVEVWLPVVRELRRNLKVLWVPRHIERSKELEALLSKENISYGLWSKEATFAQHDAIIVDAIGWLKQLYSAADLAFVGGTFDDRIGGHNLLEPLQCGVPLIFGPHIQSQSDLAERLLSMGAGCCLDKTNIVKVITFLLDHPEERAAYIQKGAMFLHEEKVAFDRTWESFKRYIPCVKI
Catalytic domain sequence
178 aa
LGIRFGFKKPEVPGTGPVAWFHGASVGETALLLPLLKRFMKEYPEWRCVVTSCTESGHENAHRLFGPLGVTTFILPLDLSIIIKPVVRAISPSLLVFSEGDCWLNFIEEAKRLGATAVIINGKLSANSCKRFTILKRFGRNYFSPVDGFLLQDEQHKARFLQLGVDKEKIQVTGNIKT
