Home/GT Families/GT30/waaA
waaA
Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13) · 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12; 2.4.99.13; 2.4.99.14)
GT30Non-model organism · annotation 4–5Fold GT-BInverting
External resources
Identification and annotation
| CAZy family | GT30 · CAZy entry |
|---|
| Gene symbol | waaA |
|---|
| Synonyms / alternate names | - gseA
- kdtA
- Kdo(2)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Kdo-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
- Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
|
|---|
| UniProt accession | Q3KMF4 |
|---|
| NCBI Gene ID | not curated |
|---|
| Source species | Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13) |
|---|
| Taxonomic domain | Bacteria |
|---|
| UniProt annotation level | 4 |
|---|
Function and localisation
| Enzyme function | 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12; 2.4.99.13; 2.4.99.14) |
|---|
| Subcellular location | not curated |
|---|
Structure and mechanism
| Fold type | GT-B |
|---|
| Catalytic mechanism | Inverting |
|---|
| Cation dependence | No |
|---|
| Oligomeric state | not curated |
|---|
| PDB structures | not curated |
|---|
Donor and acceptor specificity
| Sugar nucleotide donor | CMP-3-deoxy-beta-D-manno-octulosonate |
|---|
| Donor CCD code(s) | not curated |
|---|
| Acceptor substrate(s) | - lipid IVA (E. coli)
- alpha-Kdo-(2->6)-lipid IVA (E. coli)
- alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)
|
|---|
| Acceptor CCD / GlycoCT | not curated |
|---|
Protein sequences
Full protein sequence
431 aa
MIRRWLTSRLYDAFLVCAFFVSAPRIFYKVFFHGKYIDSWKIRFGVQKPFVKGEGPLVWFHGASVGEVSLLAPLLNRWREEFPEWRFVVTTCSEAGVHTARRLYESLGATVFVLPLDLSCIIKSVVRKLAPDIVIFSEGDCWLHFLTESKRLGAKAFLINGKLSEHSCKRFSFLKRLGRNYFAPLDLLILQDELYKQRFMQIGISSDKIHVTGNMKTFIESSLATNRRDFWRAKLQISSQDRLIVLGSVHPKDVEVWAEVVSHFHNSSTKILWVPRHLEKLKEHAKLLEKAGILFGLWSQGASFRQYNSLIMDAMGVLKDIYSAADIAFVGGTFDPSVGGHNLLEPLQKEVPLMFGPYIYSQSVLAEKLREKEAGLSVNKETLLDVVTDLLQNEKNRQAYIEKGKSFLKQEENSFQQTWEILKSQITCMKI
Catalytic domain sequence
179 aa
SWKIRFGVQKPFVKGEGPLVWFHGASVGEVSLLAPLLNRWREEFPEWRFVVTTCSEAGVHTARRLYESLGATVFVLPLDLSCIIKSVVRKLAPDIVIFSEGDCWLHFLTESKRLGAKAFLINGKLSEHSCKRFSFLKRLGRNYFAPLDLLILQDELYKQRFMQIGISSDKIHVTGNMKT
