Home/GT Families/GT31/B3GALNT1
B3GALNT1
Sus scrofa · UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79)
GT31Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT31 · CAZy entry |
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| Gene symbol | B3GALNT1 |
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| Synonyms / alternate names | - B3GALT3
- Beta-1,3-galactosyltransferase 3
- Beta-3-Gx-T3
- Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase
- Globoside synthase
- UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
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| UniProt accession | Q864U6 |
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| NCBI Gene ID | 397634 |
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| Source species | Sus scrofa |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) |
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| Subcellular location | Golgi apparatus membrane |
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mg2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-N-acetyl-alpha-D-galactosamine |
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| Donor CCD code(s) | UD2 |
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| Acceptor substrate(s) | a globoside Gb3Cer (d18:1(4E)) |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
331 aa
MAPALPITLPSKMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFHFTLREHSNCSHQNPFLVILVTSHPADVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKVLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVTEFCPNARYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFYQKTHISYQEYPFKVFPPYCSGLGYIMSRDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
Catalytic domain sequence
192 aa
KARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKVLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVTEFCPNARYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFYQKTHISYQEYPFKVFPPYCSGLGYIMSRDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVDIHI
