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pvg3
Schizosaccharomyces pombe (strain 972 / ATCC 24843) · Beta-1,3-galactosyltransferase pvg3 (EC 2.4.1.134)
GT31Non-model organism · annotation 4–5Fold GT-AInverting
External resources
Identification and annotation
| CAZy family | GT31 · CAZy entry |
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| Gene symbol | pvg3 |
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| Synonyms / alternate names | - mug49
- Meiotically up-regulated gene 49 protein
- Pyruvylated Gal-beta-1,3-epitope synthesis protein 3
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| UniProt accession | Q9USX0 |
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| NCBI Gene ID | 2540827 |
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| Source species | Schizosaccharomyces pombe (strain 972 / ATCC 24843) |
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| Taxonomic domain | Eukaryota |
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| UniProt annotation level | 4 |
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Function and localisation
| Enzyme function | Beta-1,3-galactosyltransferase pvg3 (EC 2.4.1.134) |
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| Subcellular location | - Endoplasmic reticulum membrane
- Golgi apparatus, Golgi stack membrane
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Structure and mechanism
| Fold type | GT-A |
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| Catalytic mechanism | Inverting |
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| Cation dependence | Yes (Mn2+) |
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| Oligomeric state | not curated |
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| PDB structures | not curated |
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Donor and acceptor specificity
| Sugar nucleotide donor | UDP-alpha-D-galactose |
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| Donor CCD code(s) | GDU |
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| Acceptor substrate(s) | 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] |
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| Acceptor CCD / GlycoCT | not curated |
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Protein sequences
Full protein sequence
378 aa
MFSNSKKKIFLYVLIAGVATFSFAFLVLNRLQAEEHSLAYVENLFLDPFIKQNESLAHANDRPFKLYLGIFSQAKNVDRRNFLRTDYNEYIKEFAVNDTVDVRFILGLPENEQELATIREEQRTYGDLAVLPIPENVDAGKSIVYFQTFLEGYQPFPLFSELADNLIMPSTQFHGSFIYNQSIKTYELPGMKEFQDLGEPKHDYDFIVKADDDSFLNLPRLFEMLKEHVGKSRFYFGRDCTRRELPTAVRDFPYMCGFFYIVSPDMAYEVAKRRNIIIPFEDAQTGYSIYLSGNVKNAEFSKCTLYDLILPNEGFNYRQSYLRIDAIAVHKLKSIPLLSTVSNWFKKMYEHRANCSALIETERLSCLQATIPLPSLDV
Catalytic domain sequence
not curated
