BioF:GREAT aims to resolve the issue that glycans, despite being present in all living organisms, are undertaught in the classroom and understudied at the research bench. The BioF:GREAT will take major steps towards addressing these deficiencies by developing new research, technologies, and instructional experiences that span across the tree of life to democratize glycoscience and bring it into mainstream life science research and education. By providing equitable access to advanced infrastructure and resources in glycoscience, BioF:GREAT will advance scientific inquiry and education in biosciences across all kingdoms of life.