Publications in 2026

Berardinelli SJ, Kadirvelraj R, Luther KB, Gao Z, Chapla D, Huang C, Tehrani DM, Zhang A, Moremen KW, Wood ZA, Haltiwanger RS. Crystal structure of a β1,3-Glucosyltransferase reveals an unusual substrate recognition by a two-domain GT-A fold glycosyltransferase. J Biol Chem. 2026 Aug 10:113418. doi: 10.1016/j.jbc.2026.113418. Epub ahead of print. PMID: 42575440.

Tiwari M, Dolan EL. Building Bridges: A Story of How Institutional Investment in Discipline-Based Education Research Enables Evidence-Based Teaching in Biochemistry Education. Biochem Mol Biol Educ. 2026 Jul 16. doi: 10.1002/bmb.70066. PMID: 42464043.

Tehrani D, Cortiella-Valls N, Huang C, Chapla D, Zheng Z, Venkat A, O’Boyle B, Kannan N, Perez C, Moremen KW. Structural basis of chondroitin sulfate backbone polymer synthesis. Nat Commun. 2026 May 27. https://doi.org/10.1038/s41467-026-73361-0. Epub ahead of print. PMID: 42204168.

Kamatar A, Villalobos JA Jr, Hayden CC, Rodriguez Flores FG, Archer-Hartmann S, Azadi P, Belardi B, Parekh SH, Stachowiak JC. Inhibition of endocytosis by glycans arises from steric rather than electrostatic repulsion. Biophys J. 2026 Apr 21;125(8):1941-1957. doi: 10.1016/j.bpj.2026.03.026. Epub 2026 Mar 13. PMID: 41832605.

Wang S, Lin TH, Antonopoulos A, Kikuchi C, Chapla DG, Valverde P, Moremen KW, Haslam SM, Wilson IA, Paulson JC. Chemoenzymatic Synthesis of N-Linked Glycan Receptors of H1N1 Influenza Virus on Human Airway Epithelial Cells. J Am Chem Soc. 2026 Mar 25;148(11):12126-12138. doi: 10.1021/jacs.6c00093. Epub 2026 Mar 11. PMID: 41810832.
Relano-Rodriguez I, Du J, Lin ZJ, Kerwin M, Tarquis-Medina M, Urbano E, Cui J, Watkins M, Lavine CL, Zhao P, Habib R, Agostino C, Ghosh S, Park J, Boroughs C, Walsh AA, Melo MB, Shukla N, Shaw GM, Hahn BH, Irvine DJ, Wells L, Weiner DB, Seaman MS, Kulp DW, Veazey RS, Pallesen J, Escolano A. Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates. Nat Immunol. 2026 Mar;27(3):586-599. doi: 10.1038/s41590-025-02408-z. Epub 2026 Feb 3. PMID: 41634485; PMCID: PMC12956587.
Eletsky A, Huang C, Miao Y, Moremen KW, Morris LC, Prestegard JH. Conformational Preferences for N-Glycans at the Surface of CEACAM1-Ig1. ACS Chem Biol. 2026 Jan 16;21(1):130-140. doi: 10.1021/acschembio.5c00746. Epub 2025 Dec 19. PMID: 41416709; PMCID: PMC12813971.

Publications in 2025

Weidler S, Bundgaard O, Hessefort M, Rädisch M, Graf CGF, Lam K, Neubauer VJ, Eisenreich J, Köhler L, Moremen KW, Steentoft C, Clausen H, Huang TY, Hung SC, Steegborn C, Weyand M, Unverzagt C. Human Proteoglycan Linkage Region Glycosyltransferases are Dimeric and Show Unexpected Specificities. Angew Chem Int Ed Engl. 2026 Jan 16;65(3):e16855. doi: 10.1002/anie.202516855. Epub 2025 Nov 29. PMID: 41316887; PMCID: PMC12811666.
Johnson KA, Goswami HN, Catchpole RJ, Ahmadizadeh F, Zhao P, Wells L, Li H, Terns MP. A phage-encoded anti-CRISPR protein co-opts host enolase to prevent type III CRISPR immunity. Nat Microbiol. 2025 Dec;10(12):3162-3175. doi: 10.1038/s41564-025-02178-2. Epub 2025 Nov 11. PMID: 41219509; PMCID: PMC12811900.
Huang C, Moremen KW. Editor’s Choice JAAG: a JSON input file assembler for AlphaFold 3 with glycan integration. Glycobiology. 2025 Dec 17;36(1):cwaf083. doi: 10.1093/glycob/cwaf083. PMID: 41358904; PMCID: PMC12718408.
Lu JD, Zhao P, Prasad A, Gupta N, Gravel N, Shidhaye T, Wells L, Katiyar S, Kannan N. Deciphering the unique autoregulatory mechanisms and substrate specificity of the understudied DCLK3 kinase linked to neurodegenerative diseases. J Biol Chem. 2025 Oct;301(10):110664. doi: 10.1016/j.jbc.2025.110664. Epub 2025 Sep 1. PMID: 40902973; PMCID: PMC12509982.
Huang C, Kannan N, Moremen KW. Modeling glycans with AlphaFold 3: capabilities, caveats, and limitations. Glycobiology. 2025 Sep 3;35(10):cwaf048. doi: 10.1093/glycob/cwaf048. PMID: 40874547; PMCID: PMC12448869.
Hou C, Zhang H, Deng J, Wang X, Byers S, Levi M, Pak DTS, Moremen KW, Pei H, Hart GW, Ma J. Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics. Mol Cell Proteomics. 2025 Oct;24(10):101064. doi: 10.1016/j.mcpro.2025.101064. Epub 2025 Aug 28. PMID: 40885482; PMCID: PMC12506516.
Clarke D, Costanzo A, Sharma S, Kain L, Moremen KW, Pettus J, Domissy A, Wu P, Nguyen-Ngoc KV, Berti D, George SC, Hughes CCW, Sander M, Teyton L. A vascular-associated fibroblastic cell controls pancreatic islet immunity. Cell Rep. 2025 Sep 23;44(9):116189. doi: 10.1016/j.celrep.2025.116189. Epub 2025 Aug 28. PMID: 40884792; PMCID: PMC12539416.
Surber SM, Hsieh C, Na L, Harding SA, Tsai CJ. An updated sulfate transporter phylogeny uncovers a perennial-specific subgroup associated with lignification. Tree Physiol. 2025 Nov 28;45(13):114-128. doi: 10.1093/treephys/tpaf080. PMID: 40643194; PMCID: PMC12666378.
Oh SH, Gudipati DR, Shi W, Zhao P, Wu W, Boyington JC, Nariya HK, McGhee EG, Azzam T, Raghunathan V, Yang C, Yang C, Lee C, Kim JD, Zhou T, Mascola JR, Wells L, Kong R. Novel HIV-1 fusion peptide immunogens using glycan-engineered alphavirus-like particles. NPJ Vaccines. 2025 Nov 14;10(1):232. doi: 10.1038/s41541-025-01288-6. PMID: 41238582; PMCID: PMC12618464.

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