Internal projects
Internal projects are collaborations between BioF:GREAT laboratories at the University of Georgia. They span structural glycobiology, glycoproteomics, glycan engineering, computational method development and education research, and they exercise the same instrumentation and analytical pipelines that are available to external users through the User Facility.
Current internal projects
Influenza Crystallography
Labs: Wood, Ramirez and Souza-Rajao
Thermophiles Under the Sea
Labs: Kannan, Wells, Azadi and Terns
Extracellular vesicle proteome
Labs: Wells and Yao
O-GlcNAc and Additional PTMs in Neurodegeneration
Labs: Wells and Kanthasamy
Xylosyltransferase Characterization
Labs: Moremen and Wells
Secretome of glycosaminoglycans
Labs: Wells and Weiss
Purification of glycosyltransferases in bacteria
Labs: Wells and Ramirez
Phosphorylation of human ferrochelatase
Medlock and Wells Lab
O-fucosylation in slime mold organisms
Labs: Wells and West
Structural basis of chondroitin sulfate backbone polymer synthesis
Labs: Moremen and Perez
Structural basis of pectin polysaccharide glycoenzymes
Labs: Moremen, Perez and Mohnen
Multienzyme complexes of GAG synthesis
Labs: Moremen, Weiss, Perez and Ramirez
Lectin identification of fungal pathogens
Labs: Moremen and Meagher
Structure of an unusual human glycosyltransferase
Labs: Wood, Moremen and Haltiwanger
Glyco videos for students (Sweet Spot Guidelines)
Labs: Wells and Dolan
HTP glycomics and glycoproteomics
Labs: Azadi and User Facility
AI/ML based prediction of glycoenzyme donor substrates
Lab: Kannan
Evolution of the N-glycosylation pathway
Labs: Urbanowicz and Kannan
Agentic-AI tools for glycoenzyme annotation
Lab: Kannan
AI/ML based prediction of PTMs and site specific heterogeneity
Lab: Kannan and Wells
Fragmentation of N-glycans using novel MS techniques
Lab: Azadi
Designing of glycoenzymes using AI/ML
Labs: Kannan and Moremen
Glycoproteomic worksheet
Lab: Azadi