External projects
External projects pair BioF:GREAT laboratories with collaborators at other universities, national laboratories, government agencies and companies. They are the primary route through which the initiative’s glycoanalytic, enzymatic and computational capabilities reach the wider research community. To propose one, see user proposals.
Glycoproteomics and modification mapping
Glycan analysis of a cell-adhesion receptor
Lead laboratory: Wells
Glycan analysis of a viral surface protein
Lead laboratory: Wells
Glycan labelling in a neurological disease model
Lead laboratory: Wells
Glycoform conservation on a viral envelope protein
Lead laboratory: Wells
Glycopeptide analysis of an engineered archaeal protein
Lead laboratory: Azadi
Interplay between two modifications in a model plant
Lead laboratories: Wallace, Wells
Intracellular glycosylation in an enteric parasite
Lead laboratories: West, Wells
Intracellular glycosylation proteomics
Lead laboratory: Moremen
O-fucosylation in a free-living amoeba
Lead laboratories: West, Wells
O-fucosylation in an enteric parasite
Lead laboratories: West, Wells
O-mannosylation of a receptor phosphatase family
Lead laboratory: Wells
N-glycan site mapping in a common cell line Completed
Lead laboratory: Azadi
Glycomics and analytical methods
Native mass spectrometry methods for sialylated glycans
Lead laboratory: Moremen
A plant lectin in root nodule symbiosis Completed
Lead laboratory: Azadi
A sugar marker in a congenital glycosylation disorder Completed
Lead laboratory: Azadi
Antibody N-glycans and receptor binding Completed
Lead laboratory: Moremen
Antibody glycans in a veterinary species Completed
Lead laboratory: Azadi
Glycan effects on cell-surface uptake Completed
Lead laboratory: Azadi
Glycans in immune tolerance at the maternal interface Completed
Lead laboratory: Azadi
Glycomics of a marine symbiosis organ Completed
Lead laboratory: Azadi
Glycomics of an invertebrate secretion Completed
Lead laboratory: Azadi
Glycomics of insect glycosylation mutants Completed
Lead laboratory: Azadi
Glycosylation changes in epithelial and tumour cell lines Completed
Lead laboratory: Azadi
Glycosylation in germ-free animal models Completed
Lead laboratory: Azadi
Host glycans as a bacterial nutrient source Completed
Lead laboratory: Moremen
Quantifying proteoglycan markers in blood Completed
Lead laboratory: Azadi
Tissue-specific glycomics in an insect model Completed
Lead laboratory: Azadi
Glycoenzyme expression and engineering
A glycosyltransferase in a parasitic protozoan
Lead laboratories: West, Azadi
Characterisation of plant esterases
Lead laboratories: Urbanowicz, Moremen
Chemoenzymatic study of lectin–glycan interactions
Lead laboratory: Moremen
Enzyme engineering of plant glycosyltransferases
Lead laboratories: Moremen, Urbanowicz
Glycopeptide reference standards with an instrument manufacturer
Lead laboratories: Wells, Moremen
A plant polysaccharide acetyltransferase Completed
Lead laboratories: Moremen, Urbanowicz
Extended glycan chains on viral receptors Completed
Lead laboratory: Moremen
O-glycan transferase specificity Completed
Lead laboratory: Moremen
Synthetic glycan receptors for a respiratory virus Completed
Lead laboratory: Moremen
Education and outreach research
Education materials inventory
Lead laboratory: Dolan
Introductory glycoscience teaching module
Lead laboratory: Dolan
Glycoscientist profiles Completed
Lead laboratory: Dolan
Training in glycoenzyme purification and glycomics Completed
Lead laboratories: Azadi, Moremen
Visiting scholar training in mammalian expression Completed
Lead laboratory: Moremen