JAAG Software: A Glycan Modeling tool Developed by BioF:GREAT Team Members

Chin Huang Develops JAAG Software

Chin Huang, a graduate student in Dr. Kelley Moremen’s BioF:GREAT laboratory, has developed a web-based tool that helps glycan modeling by Alphafold 3.

AlphaFold 3 can accurately model glycans with proper stereochemistry only when using the BAP+CCD syntax, but manually creating these inputs is tedious and error-prone. To streamline the process, JAAG—a lightweight, user-friendly web tool—automates the conversion of glycans drawn by users into BAP+CCD syntax. This makes it easier for scientists to model glycoproteins and glycan–protein interactions, helping even AlphaFold 3 beginners generate reliable, stereochemically valid structures effortlessly.

Link to JAAG Manuscript

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