Democratizing Glycoscience by increasing accessibility to resources, education, and training

Highlighted Projects of BioF:GREAT

Internal Project

Thermophiles Under the Sea: Glycans in hydrothermal vents
External Project

Communication Breakdown: O-fucose and O-GlcNAc in Plants
Biotech

Glycopeptide Standards: Working with Bruker

List of All BioF:GREAT Projects

Internal BioF:GREAT Projects

  • Influenza Crystallography Project (Zac Wood, Ana Ramirez and the Souza-Rajao Lab)
  • Thermophiles Under the Sea Project (Kannan, Wells, Azadi and the Terns Lab)
  • Extracellular vesicle proteome (Wells, and the Yao Lab)
  • O-GlcNAc and Additional PTMs in Neurdegeneration (Wells, and the Kanthasamy Lab)
  • Xylosyltransferase Characterization (Moremen and the Wells Lab)
  • Secretome of glycosaminoglycans (Wells and the Weiss Lab)
  • Purification of glycosyltransferases in bacteria (Wells and the Ramirez Lab)
  • Phosphorylation of human ferrochelatase (Wells and Medlock Lab)
  • O-fucosylation in slime mold organisms (Wells and West Lab)
  • Structural basis of chondroitin sulfate backbone polyme synthesis (Moremen and Perez Lab)
  • Structural basis of pectin polysaccharide glycoenzymes (Moremen, Perez and Mohnen Labs)
  • Multienzyme complexes of GAG synthesis (Moremen, Weiss, Perez and Ramirez Labs)
  • Lectin identification of fungal pathogens (Moremen and Meagher Lab)
  • Structure of an unusual human glycosyltransferase (Wood, Moremen and Haltiwanger Lab)
  • Glyco videos for students (Sweet Spot Guidelines) (Wells, and Dolan Lab)
  • HTP glycomics and glycoproteomics (Azadi Lab and User Facility)
  • AI/ML based prediction of glycoenzyme donor substrates (Kannan Lab)
  • Evolution of the N-glycosylation pathway (Urbanowicz and Kannan Lab)
  • Agentic-AI tools for glycoenzyme annotation (Kannan Lab)
  • AI/ML based prediction of PTMs and site specific heterogeneity (Kannan and Wells Lab)
  • Fragmentation of N-glycans using novel MS techniques (Azadi Lab)
  • Designing of glycoenzymes using AI/ML (Kannan and Moremen Lab)
  • Glycoproteomic worksheet (Azadi Lab)

External BioF:GREAT Projects

  • Mechanisms of glycan-induced immune tolerance (Azadi and Rizzuto Lab)
  • Ribose and CDG patients (Azadi and Starosta Lab)
  • Glycan engineering of viral fusion peptide immunogen (Wells and Kong Lab)
  • Analysis of viral glyoproteins (Wells and CDC Laboratories)
  • Analysis of O-glycans on receptor proteins (Wells and Panin Lab)
  • N-linked glycan analysis of HCoVNL63 spike protein (Wells and Chiu Lab)
  • Determination of glycan heterogeneity of integrins (Wells and Serini Lab)
  • Glycogen storage defect analysis (Wells and Gentry Lab)
  • Generating glycopeptide standards (Wells Lab and Bruker Company)
  • Antibody N-glycans and binding to receptors (Moremen and Boons Lab)
  • Polypeptide GalNAc transferase specificities (Moremen and Gerken Lab)
  • O-GlcNAc glycoproteomics (Moremen and Ma Lab)
  • Chemoenzymatic approaches to lectin-glycan and ligand interactions (Moremen and Wu Lab)
  • Enzyme engineering of plant glycosyltransferases (Moremen, Urbanowicz and Scheller Lab)
  • O-acetyltransferases and plant glycoproteins (Urbanowicz, Moremen and Wasczcak Lab)
  • Cysteine-rich domains and host immunity (Urbanowicz, Moremen and Muchero Lab)
  • Communication between O-GlcNAc and O-Fuc in plants (Wallace, Wells and Roberts Lab)
  • Glycoscientist Spotlights (Dolan other Glycoscience Labs at multiple Universities)
  • Introduction to glycoscience education modules (Dolan and students from multiple Universities)
  • Humans in Glycobiology: Tree of Life (Dolan and multiple Universities)
  • Glycoeducation materials inventory (Dolan and students from multiple Universities)
  • Glycomic Analysis of Squid Species (Azadi and Nyholm Lab)
  • Quantification of GAGs from Serum and Plasma (Azadi and Bisiau Lab)
  • Glycosylation analysis of benign and malignant cancer cells (Azadi and Chen Lab)
  • Unusual glycan modifications on GPI's and GIPL's (West, Azadi and Heise Lab)
  • O-glycome of a rare Protozoa (West, Wells and Samuelson Lab)
  • O-glycome of a disease causing Protozoa (West, Wells and Samuelson Lab)
  • O-glycome of a disease causing Apicomplexa (West, Wells and Samuelson Lab)
  • Glycoform conservation of bNABs and targeted viruses (West, Wells and Avci Lab)

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