JAAG software released for AlphaFold 3 glycan modelling
Chin Huang, a graduate student in Dr. Kelley Moremen’s BioF:GREAT laboratory, has developed a web-based tool that helps glycan modeling by Alphafold 3.
AlphaFold 3 can accurately model glycans with proper stereochemistry only when using the BAP+CCD syntax, but manually creating these inputs is tedious and error-prone. To streamline the process, JAAG—a lightweight, user-friendly web tool—automates the conversion of glycans drawn by users into BAP+CCD syntax. This makes it easier for scientists to model glycoproteins and glycan–protein interactions, helping even AlphaFold 3 beginners generate reliable, stereochemically valid structures effortlessly.